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Erectile Dysfunction
Future Treatments for ED

Future treatments for erectile dysfunction focus on providing medications that are more effective, work rapidly, and have fewer, if any, side effects than currently available treatments. Currently there are three oral medications available to treat ED - Cialis, Levitra and Viagra . A number of pharmaceutical companies are researching new treatments for ED, and many new options may be just around the corner. These include:

Cialis (tadalafil):Cialis works like Viagra, but stays in the bloodstream longer, between 24-36 hours. As a result, a man is able to have sex again during that time without taking more medication.

Uprima: Still undergoing clinical trials, Uprima comes in a tablet form that dissolves under the tongue. Uprima works by stimulating the brain chemical dopamine, which heightens sexual interest and sensations. A small number of people passed out after taking Uprima, so its release in the U.S. is on hold; however, it is currently available in Europe. Clinical trials are also currently being conducted on a nasal spray form of this drug.

Topiglan: Still under investigation, if Topiglan were to be approved by the FDA, it would be the first topical medication applied to the penis to treat ED. Topliglan uses the same drug that is used in injection therapy and suppository therapy, alprostadil. If Topligan proves safe and effective, injection and suppository therapy would no longer be required. The man could get the same benefit by applying the medication topically. Initial clinical trial results yield few side effects.

Alibra: Still under review by the FDA, Alibra is similar to alprostadil, but it lasts longer and has a built-in painkiller.

Reviewed by the doctors at the Glickman Urological Institute at The Cleveland Clinic.

Edited by Charlotte Grayson, MD, WebMD, May 2004
Portions of this page © The Cleveland Clinic 2000-2004

 

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