Cialis starts working much Quicker than Viagra, sometimes in 16 minutes, and lasts 24 - 36 hours. In comparison, Viagra normally works for only two - four hours after about a delay of an hour. Doctors attribute Cialis' longer-term effects to a difference in the rate at which it is chemically active in the bloodstream and eliminated from the body compared with Viagra.

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The drug works in a similar fashion to Viagra by targeting the same enzyme that can increase blood flow to the penis. But when Compared with Viagra, Cialis has a different molecular structure

As is the case with Viagra, 80% or more of men with erectile function (ED) are able to achieve an erection with Cialis use and three out of four are able to achieve sexual intercourse. But in one Cialis study, 59% of previously impotent men were still able to have sex  up to 36 hours after using it.

But some major differences in the drugs surfaced during clinical trials. Cialis might work even after eating a full meal, while Viagra works best on an empty stomach.

Cialis' makers also say their drug has fewer side effects than Viagra, which some users complain causes abnormal vision, indigestion and diarrhea.